This document is the second in a four part series exploring health related stigma. It was published in 2011 by the International Federation of Anti-Leprosy Associations (ILEP) and was published to be used by all managers, health and social workers and service staff who have to deal with stigma in leprosy and other health conditions. The Guides series provides evidence-based and best-practice information from different disciplines, and recommendations for field workers on how to reduce stigma against and among affected persons and in the community. This specific guide explores when and how to assess stigma using qualitative and quantitative methods.